Barrier-enforcing measures as treatment principle in allergic rhinitis: a systematic review. (June 2014)

• Record Type: Journal Article
• Authors: Andersson, Morgan; Greiff, Lennart; Ojeda, Pedro; Wollmer, Per
• Is Part Of: Current medical research and opinion. Volume 30:Number 6(2014:Jun.)
• Page Start: 1131
• Page End: 1137
• Publication Date: 2014-06
• Subjects: Clinical medicine -- Periodicals; Therapeutics -- Periodicals; 615.5
• DOI: 10.1185/03007995.2014.882299
• Languages: English
• ISSNs: 0300-7995

Abstract

<abstract> <title>Abstract</title> <sec id="ss1"> <title>Background and objectives</title> <p>Barrier-enforcing measures have been suggested as treatment options for allergic rhinitis. This review identifies and describes the literature on the subject.</p> </sec> <sec id="ss2"> <title>Methods</title> <p>Relevant publications were searched for in the PubMed database (search entries: 'allergic rhinitis' and 'treatment'). The evaluation comprised condition (seasonal or perennial allergic rhinitis), type of intervention, duration of treatment, study design, peer review status or not, number of test subjects, type of allergen exposure, and outcome in terms of effects or not on nasal symptoms of allergic rhinitis.</p> </sec> <sec id="ss3"> <title>Results</title> <p>Fifteen studies were either identified in the PubMed database search or from the reference lists of identified publications. Seven were placebo-controlled, randomized, and peer-reviewed, and symptom-reducing effects were reported by all of these reports. Limitations of this review reflect that the remainder of the studies had inferior designs, particularly lack of placebo control.</p> </sec> <sec id="ss4"> <title>Conclusions</title> <p>Barrier-enforcing measures as achieved by nasal administrations of cellulose powder and microemulsions, respectively, have symptom-reducing effects in allergic rhinitis.</p> </sec> </abstract>