Antihypertensive drug therapy in patients with African ancestry. (June 2014)

• Record Type: Journal Article
• Authors: Rizos, Christos V; Elisaf, Moses S
• Is Part Of: Expert opinion on pharmacotherapy. Volume 15:Number 8(2014)
• Page Start: 1061
• Page End: 1064
• Publication Date: 2014-06
• Subjects: Chemotherapy -- Periodicals; 615.5805
• DOI: 10.1517/14656566.2014.903921
• Languages: English
• ISSNs: 1465-6566

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>Blood pressure plays an important role in the development and progression of cardiovascular disease. Among hypertensive patients, those with African ancestry present with distinctive metabolic characteristics and cardiovascular profile. As a result, the need for individualized antihypertensive treatment strategy is of great importance. Lifestyle modifications as well as low sodium diet will play a major role in controlling blood pressure. The initiation of antihypertensive treatment with calcium channel blockers or diuretics is favored over angiotensin receptor blockers, angiotensin-converting enzyme inhibitors or β-blockers, provided no specific indications for the latter drugs are present. Moreover, the need for combination treatment often arises. As a result, the effective and safe hypertension management of patients with African ancestry is of critical importance for reducing cardiovascular morbidity and mortality.</p> </abstract>