Molecular modelling of HLA‐B*35:132. (9th January 2014)

• Record Type: Journal Article
• Authors: Longhi, E.; Crivello, P.; Mantovani, M.; Frison, S.; Fleischhauer, K.; Crespiatico, L.; Piccolo, G.; Poli, F.
• Is Part Of: International journal of immunogenetics. Volume 41:Number 3(2014:Jun.)
• Page Start: 195
• Page End: 197
• Publication Date: 2014-01-09
• Subjects: Immunogenetics -- Periodicals; 571.9648
• DOI: 10.1111/iji.12105
• Languages: English
• ISSNs: 1744-3121

Abstract

<abstract abstract-type="main" id="iji12105-abs-0001"> <title>Summary</title> <p>Here we describe the molecular modelling of the new variant HLA‐B*35:132. This allele shows one mismatch with B*35:01:01:01 in exon 3 at position 575 where a T is substituted by a C, which implies an amino acidic change from Leucine to Proline. This seems not to alter the molecular structure and not to compromise the HLA complex and T‐cell receptor interaction.</p> </abstract>