Genital infection caused by Entamoeba histolytica confirmed by polymerase chain reaction analyses. Issue 5 (21st April 2014)

• Record Type: Journal Article
• Authors: Asano, Hiroshi; Kaneuchi, Masanori; Furuta, Itsuko; Yamaya, Yukie; Hatanaka, Kanako C.; Takeda, Mahito; Matsuno, Yoshihiro; Sakuragi, Noriaki
• Is Part Of: Journal of obstetrics and gynaecology research. Volume 40:Issue 5(2014:May)
• Page Start: 1441
• Page End: 1444
• Publication Date: 2014-04-21
• Subjects: Gynecology -- Periodicals; Obstetrics -- Periodicals; 618.1005
• DOI: 10.1111/jog.12351
• Languages: English
• ISSNs: 1341-8076

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <p> <italic>Entamoeba histolytica</italic> is estimated to infect approximately 1% of the global population. In Japan, the prevalence of amebic dysentery has been increasing, with more than 800 patients newly diagnosed annually. However, genital infection with <italic>E. histolytica</italic> is uncommon even in endemic areas. We present a case of vaginitis caused by <italic>E. histolytica</italic>. A 50‐year‐old Japanese woman without history of overseas travel presented to a nearby clinic with increased vaginal discharge. She had hemorrhagic erosion at the uterine cervix with yellowish vaginal discharge, and was referred to our hospital for exclusion of malignancy. Cervical cytology revealed periodic acid‐Schiff‐positive protozoa not aggregating around squamous cells, and thus amebic vaginitis was suspected. We performed polymerase chain reaction (PCR) analyses and identified <italic>E. histolytica</italic>. The vaginitis was treated with metronidazole, and the disappearance of amebic protozoa was confirmed by cytology and PCR. Therefore, it may be important to obtain early diagnosis by cervical cytology and PCR.</p> </abstract>