Feasibility of T2‐weighted turbo spin echo imaging of the human prostate at 7 tesla. Issue 5 (24th June 2013)

• Record Type: Journal Article
• Authors: Maas, Marnix C.; Vos, Eline K.; Lagemaat, Miriam W.; Bitz, Andreas K.; Orzada, Stephan; Kobus, Thiele; Kraff, Oliver; Maderwald, Stefan; Ladd, Mark E.; Scheenen, Tom W. J.
• Is Part Of: Magnetic resonance in medicine. Volume 71:Issue 5(2014:May)
• Page Start: 1711
• Page End: 1719
• Publication Date: 2013-06-24
• Subjects: Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.24818
• Languages: English
• ISSNs: 0740-3194

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="mrm24818-sec-0001" sec-type="section"> <title>Purpose</title> <p>To demonstrate that high quality <italic>T</italic><sub>2</sub>‐weighted (T2w) turbo spin‐echo (TSE) imaging of the complete prostate can be achieved routinely and within safety limits at 7 T, using an external transceive body array coil only.</p> </sec> <sec id="mrm24818-sec-0002" sec-type="section"> <title>Methods</title> <p>Nine healthy volunteers and 12 prostate cancer patients were scanned on a 7 T whole‐body system. Preparation consisted of <italic>B</italic><sub>0</sub> and radiofrequency shimming and localized flip angle calibration. <italic>T</italic><sub>1</sub> and <italic>T</italic><sub>2</sub> relaxation times were measured and used to define the T2w‐TSE protocol. T2w imaging was performed using a TSE sequence (pulse repetition time/echo time 3000–3640/71 ms) with prolonged excitation and refocusing pulses to reduce specific absorption rate.</p> </sec> <sec id="mrm24818-sec-0003" sec-type="section"> <title>Results</title> <p>High quality T2w TSE imaging was performed in less than 2 min in all subjects. Tumors of patients with gold‐standard tumor localization (MR‐guided biopsy or prostatectomy) were well visualized on 7 T imaging (<italic>n</italic> = 3). The number of consecutive slices achievable within a 10‐g averaged specific absorption rate limit of 10 W/kg was ≥28 in all subjects, sufficient for full prostate coverage with 3‐mm slices in at least one direction.</p> </sec> <sec id="mrm24818-sec-0004" sec-type="section"> <title>Conclusion</title> <p>High quality T2w TSE prostate imaging can be performed routinely and within specific absorption rate limits at 7 T with an external transceive body array. <bold>Magn Reson Med 71:1711–1719, 2014. © 2013 Wiley Periodicals, Inc</bold>.</p> </sec> </abstract>