Standardization of skin cleansing in vivo: part II. Validation of a newly developed Automated Cleansing Device (ACiD). Issue 2 (4th September 2013)

• Record Type: Journal Article
• Authors: Sonsmann, F. K.; Strunk, M.; Gediga, K.; Schliemann, S.; Seyfarth, F.; Elsner, P.; Diepgen, T. L.; Kutz, G.; John, S. M.
• Is Part Of: Skin research and technology. Volume 20:Issue 2(2014)
• Page Start: 239
• Page End: 245
• Publication Date: 2013-09-04
• Subjects: Skin -- Research -- Periodicals; Skin -- Diseases -- Periodicals; Skin -- Physiology -- Periodicals; 616.5
• DOI: 10.1111/srt.12113
• Languages: English
• ISSNs: 0909-752X

Abstract

<abstract abstract-type="main" id="srt12113-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="srt12113-sec-0001" sec-type="section"> <title>Background</title> <p>Skin cleansers for occupational use are manufactured for different types and degrees of soiling without common, legally binding requirements for product testing. This leads to different, manufacturer‐specific test methods and a lack of comparable information on skin cleansing products.</p> </sec> <sec id="srt12113-sec-0002" sec-type="section"> <title>Objectives</title> <p>The aim of this investigation was to validate a newly developed standardized automated cleansing device (ACiD) for <italic>in vivo</italic> evaluation of industrial skin cleansers.</p> </sec> <sec id="srt12113-sec-0003" sec-type="section"> <title>Methods</title> <p>Two ACiD were tested regarding the intra‐ and inter‐device specific reproducibility of test results.</p> </sec> <sec id="srt12113-sec-0004" sec-type="section"> <title>Results</title> <p>Skin cleansing process carried out by the three independent washing modules which constitute an ACiD‐unit and two separate ACiD‐units led to highly comparable results. There was no significant difference between the washing modules or between the two separate ACiD‐units detected. Only different parameter settings resulted in significantly different detergency.</p> </sec> <sec id="srt12113-sec-0005" sec-type="section"> <title>Conclusions</title> <p>Intra‐ and inter‐device specific test results of an <italic>in vivo</italic> model of skin cleansing using the automated cleansing device (ACiD) were reproducible. The long‐term aim is a standardized classification of occupational skin cleansing products comparing their skin cleansing effectiveness in relation to their skin irritancy. This might then provide the basis for a rational specific product selection by consumers and may be used as a tool for future product development by manufacturers.</p> </sec> </abstract>