Electrochemical Control of the Enzymatic Polymerization of PEG Hydrogels: Formation of Spatially Controlled Biological Microenvironments. Issue 4 (30th October 2013)

• Record Type: Journal Article
• Authors: Milleret, Vincent; Simona, Benjamin R.; Lienemann, Philipp S.; Vörös, János; Ehrbar, Martin
• Is Part Of: Advanced healthcare materials. Volume 3:Issue 4(2014:Apr.)
• Page Start: 508
• Page End: 514
• Publication Date: 2013-10-30
• Subjects: Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201300479
• Languages: English
• ISSNs: 2192-2640

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="adhm201300479-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Control of pH gradient profile at the electrode–electrolyte interfaces</bold> allows the control of the enzymatic PEG‐hydrogel polymerization. By tuning the solution pH, buffer capacity, and the applied current, the extent of the local inhibition and confinement of the Factor XIII‐mediated polymerization of PEG are controlled. This technology opens new perspectives for the production of 3D‐structured biological microenvironments. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg59w22zkm" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>