Assessing the impact of public health interventions on the transmission of pandemic H1N1 influenza a virus aboard a Peruvian navy ship. Issue 3 (10th February 2014)

• Record Type: Journal Article
• Authors: Vera, Delphis M.; Hora, Ricardo A.; Murillo, Anarina; Wong, Juan F.; Torre, Armando J.; Wang, David; Boulay, Darbi; Hancock, Kathy; Katz, Jacqueline M.; Ramos, Mariana; Loayza, Luis; Quispe, Jose; Reaves, Erik J.; Bausch, Daniel G.; Chowell, Gerardo; Montgomery, Joel M.
• Is Part Of: Influenza and other respiratory viruses. Volume 8:Issue 3(2014:May)
• Page Start: 353
• Page End: 359
• Publication Date: 2014-02-10
• Subjects: Influenza -- Periodicals; Respiratory infections -- Periodicals; Virus diseases -- Periodicals; Influenza, Human -- Periodicals; Respiratory Tract Diseases -- Periodicals; Virus Diseases -- Periodicals; Grippe -- Périodiques; Appareil respiratoire -- Infections -- Périodiques; Maladies à virus -- Périodiques; 616.203
• DOI: 10.1111/irv.12240
• Languages: English
• ISSNs: 1750-2640

Abstract

<abstract abstract-type="main" id="irv12240-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="irv12240-sec-0001" sec-type="section"> <title>Background</title> <p>Limited data exist on transmission dynamics and effectiveness of control measures for influenza in confined settings.</p> </sec> <sec id="irv12240-sec-0002" sec-type="section"> <title>Objectives</title> <p>To investigate the transmission dynamics of a 2009 pandemic H1N1 influenza A outbreak aboard a Peruvian Navy ship and quantify the effectiveness of the implemented control measures.</p> </sec> <sec id="irv12240-sec-0003" sec-type="section"> <title>Methods</title> <p>We used surveillance data and a simple stochastic epidemic model to characterize and evaluate the effectiveness of control interventions implemented during an outbreak of 2009 pandemic H1N1 influenza A aboard a Peruvian Navy ship.</p> </sec> <sec id="irv12240-sec-0004" sec-type="section"> <title>Results</title> <p>The serological attack rate for the outbreak was 49·1%, with younger cadets and low‐ranking officers at greater risk of infection than older, higher‐ranking officers. Our transmission model yielded a good fit to the daily time series of new influenza cases by date of symptom onset. We estimated a reduction of 54·4% in the reproduction number during the period of intense control interventions.</p> </sec> <sec id="irv12240-sec-0005" sec-type="section"> <title>Conclusion</title> <p>Our results indicate that the patient isolation strategy and other control measures put in place during the outbreak reduced the infectiousness of isolated individuals by 86·7%. Our findings support that early implementation of control interventions can limit the spread of influenza epidemics in confined settings.</p> </sec> </abstract>