Ex vivo laser thermoplasty of whole costal cartilages. Issue 4 (24th February 2014)

• Record Type: Journal Article
• Authors: Sviridov, Alexander P.; Zakharkina, Olga L.; Ignatieva, Natalia Yu.; Vorobieva, Natalia N.; Bagratashvili, Nodar V.; Plyakin, Vladimir A.; Kulik, Innokentii O.; Sarukhanyan, Oganes O.; Minaev, Vladimir P.; Lunin, Valerii V.; Bagratashvili, Victor N.
• Is Part Of: Lasers in surgery and medicine. Volume 46:Issue 4(2014)
• Page Start: 302
• Page End: 309
• Publication Date: 2014-02-24
• Subjects: Lasers in medicine -- Periodicals; Lasers in surgery -- Periodicals; 617
• DOI: 10.1002/lsm.22233
• Languages: English
• ISSNs: 0196-8092

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="lsm22233-sec-0001" sec-type="section"> <title>Background and Objective</title> <p>To examine the possibilities of laser thermoplasty of whole costal cartilages for correction the human congenital chest wall deformities.</p> </sec> <sec id="lsm22233-sec-0002" sec-type="section"> <title>Study Design/Materials and Methods</title> <p> <italic>Ex vivo</italic> the samples of porcine costal cartilages were heated with lasers of differing wavelengths, including a 0.97‐μm diode laser, a 1.56‐μm erbium‐doped quartz fiber laser, and a 1.68‐μm fiber Raman laser. The dynamics of the temperature fields and the degradation of collagen in the laser‐affected regions of samples were determined by using, respectively, thermometry, trypsin treatment, and light microscopy<italic>. Ex vivo</italic> the whole mechanically deformed costal cartilages of pigs were treated by laser radiation with wavelength 1.68‐μm. The changes of cartilage shape were recorded at certain intervals over a 24‐hour period by photographing them in a fixed position with a digital camera.</p> </sec> <sec id="lsm22233-sec-0003" sec-type="section"> <title>Results</title> <p>Treatment of costal cartilage samples from 5 to 11 mm in thickness by laser radiation with 0.97, 1.56, and 1.68 μm wavelengths showed that the 1.68‐μm radiation could produce the necessary nonuniform bulk heating of the exposed sample. The altered shape of costal cartilage proved to remain stable after treatment when the laser irradiation settings used provided for the heating of a broad region within the tissue to temperatures about 80°C.</p> </sec> <sec id="lsm22233-sec-0004" sec-type="section"> <title>Conclusion</title> <p>This study demonstrates the possibilities of laser thermoplasty of whole costal cartilages for treatment of human congenital chest wall deformities. The development of novel approaches based on laser cartilage engineering techniques will enable to treat the human congenital chest wall deformities. Lasers Surg. Med. 46:302–309, 2014. © 2014 Wiley Periodicals, Inc.</p> </sec> </abstract>