Encapsulated Cobalt–Porphyrin as a Catalyst for Size‐Selective Radical‐type Cyclopropanation Reactions. Issue 17 (24th March 2014)

• Record Type: Journal Article
• Authors: Otte, Matthias; Kuijpers, Petrus F.; Troeppner, Oliver; Ivanović‐Burmazović, Ivana; Reek, Joost N. H.; de Bruin, Bas
• Is Part Of: Chemistry. Volume 20:Issue 17(2014)
• Page Start: 4880
• Page End: 4884
• Publication Date: 2014-03-24
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201400055
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A cobalt–porphyrin catalyst encapsulated in a cubic M₈L₆ cage allows cyclopropanation reactions in aqueous media. The caged‐catalyst shows enhanced activities in acetone/water as compared to pure acetone. Interestingly, the M₈L₆ encapsulated catalyst reveals size‐selectivity. Smaller substrates more easily penetrate through the pores of the "molecular ship‐in‐a‐bottle catalysts" and are hence converted faster than bigger substrates. In addition, <italic>N</italic>‐tosylhydrazone sodium salts are easy to handle reagents for cyclopropanation reactions under these conditions.</p> </abstract>