UL54 foscarnet mutation in an hematopoietic stem cell transplant recipient with cytomegalovirus disease. Issue 2 (13th March 2014)

• Record Type: Journal Article
• Authors: Gregg, K.; Hakki, M.; Kaul, D.R.
• Is Part Of: Transplant infectious disease. Volume 16:Issue 2(2014)
• Page Start: 320
• Page End: 323
• Publication Date: 2014-03-13
• Subjects: Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.12200
• Languages: English
• ISSNs: 1398-2273

Abstract

<abstract abstract-type="main" id="tid12200-abs-0001"> <title>Abstract</title> <p>We present a case of foscarnet (FOS) resistance arising from a UL54 mutation after a short duration of FOS exposure, which has not been previously described in a stem cell transplant recipient, to our knowledge. We discuss the use of FOS to treat other viral infections and the implications this may have for the development of resistance mutations and treatment of cytomegalovirus disease.</p> </abstract>