Synthesis of Diverse Azolo[c]quinazolines by Palladium(II)‐ Catalyzed Aerobic Oxidative Insertion of Isocyanides. Issue 6 (20th March 2014)

• Record Type: Journal Article
• Authors: Vlaar, Tjøstil; Bensch, Lisa; Kraakman, Jasper; Vande Velde, Christophe M. L.; Maes, Bert U. W.; Orru, Romano V. A.; Ruijter, Eelco
• Is Part Of: Advanced synthesis & catalysis. Volume 356:Issue 6(2014)
• Page Start: 1205
• Page End: 1209
• Publication Date: 2014-03-20
• Subjects: Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201301129
• Languages: English
• ISSNs: 1615-4150

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>We report the palladium(II)‐catalyzed aerobic oxidative coupling of isocyanides with various (2‐aminophenyl)azoles using air as the stoichiometric oxidant. A diverse range of medicinally valuable azolo[<italic>c</italic>]quinazolines was obtained by this new approach.</p> <p> <boxed-text content-type="graphic" position="anchor" orientation="portrait"> <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg58f9z060" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /> </boxed-text> </p> </abstract>