Catalytic Oxidation of C(sp3)H Bonds Induced by a Radical Cation Salt: Construction of 1, 4‐Dihydropyridines Using a Fragment‐Reassembly Strategy. Issue 6 (20th March 2014)

• Record Type: Journal Article
• Authors: Jia, Xiaodong; Wang, Yaxin; Peng, Fangfang; Huo, Congde; Yu, Liangling; Liu, Jing; Wang, Xicun
• Is Part Of: Advanced synthesis & catalysis. Volume 356:Issue 6(2014)
• Page Start: 1210
• Page End: 1216
• Publication Date: 2014-03-20
• Subjects: Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201300810
• Languages: English
• ISSNs: 1615-4150

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A fragment‐reassembly strategy was applied to the construction of 1, 4‐dihydropyridines and phosphorus‐substituted 1, 4‐dihydropyridines under catalytic radical cation salt‐induced C(<italic>sp</italic>)³H functionalization of glycine derivatives. Mechanistic studies show that domino C(sp)³H bond oxidation and CN bond cleavage reactions are involved.</p> <p> <boxed-text content-type="graphic" position="anchor" orientation="portrait"> <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg58f9z2w2" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /> </boxed-text> </p> </abstract>