Pelvic inflammatory disease in women with endometriosis is more severe than in those without. (20th February 2014)

• Record Type: Journal Article
• Authors: Elizur, Shai E.; Lebovitz, Oshrit; Weintraub, Adi Y.; Eisenberg, Vered H.; Seidman, Daniel S.; Goldenberg, Mordechai; Soriano, David
• Is Part Of: Australian and New Zealand journal of obstetrics and gynaecology. Volume 54:Number 2(2014)
• Page Start: 162
• Page End: 165
• Publication Date: 2014-02-20
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; 618.05
• DOI: 10.1111/ajo.12189
• Languages: English
• ISSNs: 0004-8666

Abstract

<abstract abstract-type="main" id="ajo12189-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="ajo12189-sec-0001" sec-type="section"> <title>Aims</title> <p>To determine the incidence and severity of acute pelvic inflammatory disease (PID) or tubo‐ovarian abscess (TOA) in hospitalised women with and without a history of endometriosis.</p> </sec> <sec id="ajo12189-sec-0002" sec-type="section"> <title>Methods</title> <p>Retrospective analysis of hospital records retrieved for all women hospitalised with PID or TOA between January 2008 and December 2011 in a tertiary referral centre. Women were compared with regard to a history of endometriosis for demographic, clinical and fertility data.</p> </sec> <sec id="ajo12189-sec-0003" sec-type="section"> <title>Results</title> <p>26 (15%) of the 174 women hospitalised due to PID or TOA were excluded because of age older than 45 years, leaving 148 for analysis. The mean age was 35.7 ± 9.3 years and mean duration of hospitalisation was 5.9 ± 3.7 days. The women were divided into two groups: Group 1 with endometriosis (<italic>n</italic> = 21) and Group 2 without endometriosis (<italic>n</italic> = 127). Women in Group 1 as compared with Group 2 were significantly more likely to have undergone a fertility procedure prior to being admitted to the hospital with PID (9/27 (45%) vs 22/121 (17%), <italic>P</italic> < 0.001); particularly <italic>in vitro</italic> fertilisation (IVF) (7/ 27 (33%) vs 12/121 (9%), <italic>P </italic>< 0.006); Women in Group 1 more frequently experienced a severe and complicated course involving longer duration of hospitalisation (8.8 ± 4.7 vs 4.4 ± 2.3 days, <italic>P </italic>< 0.0001) and antibiotic treatment failure (10/27 (48%) vs 8/121 (6%), <italic>P </italic>< 0.0001).</p> </sec> <sec id="ajo12189-sec-0004" sec-type="section"> <title>Conclusions</title> <p>Pelvic inflammatory disease in women with endometriosis is more severe and refractory to antibiotic treatment, often requiring surgical intervention. It is likely that endometriosis is a risk factor for the development of severe PID, particularly after IVF treatment.</p> </sec> </abstract>