Pattern of Intraocular Pressure Fluctuation in Uveitic Eyes Treated with Corticosteroids. (April 2014)

• Record Type: Journal Article
• Authors: Shrestha, Sneha; Thapa, Madhu; Shah, Dev Narayan
• Is Part Of: Ocular immunology and inflammation. Volume 22:Number 2(2014)
• Page Start: 110
• Page End: 115
• Publication Date: 2014-04
• Subjects: Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.3109/09273948.2013.824106
• Languages: English
• ISSNs: 0927-3948

Abstract

<abstract> <title>Abstract</title> <p> <italic>Purpose</italic>: To determine IOP fluctuation in uveitic eyes treated with corticosteroids.</p> <p> <italic>Design</italic>: Prospective Observational Study.</p> <p> <italic>Method</italic>: Study of 116 consecutive new uveitis patients visiting Uveitis clinic, BPKLCOS. IOP was meticulously monitored. Data was analyzed in SPSS-16 using paired samples '<italic>t</italic>-test'.</p> <p> <italic>Results</italic>: The mean IOP in all patients at presentation, at 1 week, 3 weeks and 6 weeks were respectively 14.66 mmHg, 14.72 mmHg, 14.75 mmHg and 14.93 mmHg. This progressive IOP rise was not statistically significant. Ocular hypertension was seen in 20% eyes; 64.5% were due to corticosteroids. Steroid-induced ocular hypertension was seen in 37.03% of oral group, 14.28% of posterior subtenon group, 8.57% of topical group. Antiglaucoma medications were started in 61.2% of the cases with raised IOP. None had to undergo glaucoma filtering surgery.</p> <p> <italic>Conclusion</italic>: Incidence of ocular hypertension in uveitic eyes was 20% in this study.Majority of them was corticosteroid induced. Timely medical treatment averted the necessity of surgical intervention for IOP control.</p> </abstract>