Highly Enantioselective Kinetic Resolution of Axially Chiral BINAM Derivatives Catalyzed by a Brønsted Acid1. Issue 14 (3rd March 2014)

• Record Type: Journal Article
• Authors: Cheng, Dao‐Juan; Yan, Liang; Tian, Shi‐Kai; Wu, Ming‐Yue; Wang, Lu‐Xin; Fan, Zi‐Li; Zheng, Sheng‐Cai; Liu, Xin‐Yuan; Tan, Bin
• Is Part Of: Angewandte Chemie international edition. Volume 53:Issue 14(2014)
• Page Start: 3684
• Page End: 3687
• Publication Date: 2014-03-03
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201310562
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A highly efficient strategy for the kinetic resolution of axially chiral BINAM derivatives involving a chiral Brønsted acid‐catalyzed imine formation and transfer hydrogenation cascade process was developed. The kinetic resolution provides a convenient route to chiral BINAM derivatives in high yields with excellent enantioselectivities.</p> </abstract>