Identification of lymphogranuloma venereum‐associated Chlamydia trachomatis serovars by fluorescence in situ hybridisation – a proof‐of‐principle analysis. Issue 4 (31st January 2014)

• Record Type: Journal Article
• Authors: Frickmann, Hagen; Essig, Andreas; Poppert, Sven
• Is Part Of: Tropical medicine & international health. Volume 19:Issue 4(2014:Apr.)
• Page Start: 427
• Page End: 430
• Publication Date: 2014-01-31
• Subjects: Tropical medicine -- Periodicals; Public health -- Periodicals; 616.988
• DOI: 10.1111/tmi.12271
• Languages: English
• ISSNs: 1360-2276

Abstract

<abstract abstract-type="main" id="tmi12271-abs-0001"> <title>Abstract</title> <p>We describe a proof‐of‐principle evaluation of a fluorescence <italic>in situ</italic> hybridisation (FISH) procedure to identify <italic>Chlamydia trachomatis</italic> serovars L1–L3, the causative agents of lymphogranuloma venereum, in cell cultures based on newly designed DNA probes. Rapid and easy‐to‐perform FISH could facilitate the diagnosis of lymphogranuloma venereum without nucleic acid amplification or serotyping, but requires broader evaluation studies, for example, in tropical high‐endemicity regions.</p> </abstract>