Biomedical Applications: Endocytic pH‐Triggered Degradation of Nanoengineered Multilayer Capsules (Adv. Mater. 12/2014). (March 2014)

• Record Type: Journal Article
• Authors: Liang, Kang; Such, Georgina K.; Johnston, Angus P. R.; Zhu, Zhiyuan; Ejima, Hirotaka; Richardson, Joseph J.; Cui, Jiwei; Caruso, Frank
• Is Part Of: Advanced materials. Volume 26:Number 12(2014)
• Page Start: 1947
• Page End: 1947
• Publication Date: 2014-03
• Subjects: Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201470080
• Languages: English
• ISSNs: 0935-9648

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="adma201470080-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Smart delivery systems with inbuilt biological triggers are emerging for advanced therapeutic delivery applications. F. Caruso and co‐workers describe on page 1901 the synthesis of crosslinker‐free, layer‐by‐layer (LbL) capsules that utilize cellular pH variations as a trigger to specifically deconstruct and subsequently release cargo in cells. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4xfgjnjn" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>