Encapsulation of a Catalytic Imidazolium Salt into Avidin: Towards the Development of a Biohybrid Catalyst Active in Ionic Liquids. Issue 6 (2nd January 2014)

• Record Type: Journal Article
• Authors: Gauchot, Vincent; Branca, Mathieu; Schmitzer, Andreea
• Is Part Of: Chemistry. Volume 20:Issue 6(2014)
• Page Start: 1530
• Page End: 1538
• Publication Date: 2014-01-02
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201303865
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Herein, we report the development of biohybrid catalysts that are capable of catalyzing the aldol reaction. The use of biotinylated imidazolium salts in combination with racemic or enantiomerically pure catalytic anions allowed us to study the adaptive and cooperative positioning of the anionic catalyst inside the protein. Supramolecular encapsulation of the biotinylated catalyst into avidin resulted in good selectivity for the aldol reaction performed in ionic liquid/water mixtures.</p> </abstract>