Rhodium‐Catalyzed Spirocyclic Sultam Synthesis by [3+2] Annulation with Cyclic N‐Sulfonyl Ketimines and Alkynes. Issue 49 (4th November 2013)

• Record Type: Journal Article
• Authors: Dong, Lin; Qu, Chuan‐Hua; Huang, Ji‐Rong; Zhang, Wei; Zhang, Qian‐Ru; Deng, Jin‐Gen
• Is Part Of: Chemistry. Volume 19:Issue 49(2013)
• Page Start: 16537
• Page End: 16540
• Publication Date: 2013-11-04
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201303372
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Atom‐economical addition</bold>: Rh^III‐catalyzed "Grignard‐type" cyclization between cyclic <italic>N</italic>‐sulfonyl ketimines and internal alkynes has been developed to afford multifunctional spirocyclic sultam products in high yields (up to 99 %) under mild conditions (see scheme, Cp* = pentamethylcyclopentadienyl, DCE = 1, 2‐dichloroethane).<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4t7pp1s6" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>