Conversion between Difluorocarbene and Difluoromethylene Ylide. Issue 45 (20th September 2013)

• Record Type: Journal Article
• Authors: Zheng, Jian; Lin, Jin‐Hong; Cai, Ji; Xiao, Ji‐Chang
• Is Part Of: Chemistry. Volume 19:Issue 45(2013)
• Page Start: 15261
• Page End: 15266
• Publication Date: 2013-09-20
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201303248
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The interconversion between difluoromethylene ylide and difluorocarbene is described. The difluoromethylene ylide precursor, Ph₃P⁺CF₂CO₂⁻, could be turned into an efficient difluorocarbene reagent, whereas the classical difluorocarbene reagents, HCF₂Cl and FSO₂CF₂CO₂TMS, could generate highly reactive difluoromethylene ylide. Thus the Wittig difluoro‐olefination and difluorocyclopropanation could be selectively realized by using the same reagent. In addition, the ylides obtained from different carbene sources showed different reactivity in Wittig reactions.</p> </abstract>