An Efficient Gold‐Catalyzed Domino Process for the Construction of Tetracyclic Ketoethers. Issue 44 (2nd October 2013)

• Record Type: Journal Article
• Authors: Groß, Tobias; Metz, Peter
• Is Part Of: Chemistry. Volume 19:Issue 44(2013)
• Page Start: 14787
• Page End: 14790
• Publication Date: 2013-10-02
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201302985
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Au, yeah!</bold> Catalytic amounts of gold(III)chloride allow a mild and efficient oxidative domino cyclization/cycloaddition of enyne carbonyl compounds <bold>1</bold> and <bold>4</bold> to give the tetracycles <bold>2</bold> or <bold>5</bold>, respectively, in the presence of pyridine <italic>N</italic>‐oxide <bold>3</bold> (see scheme; DCE = 1, 2‐dichloroethane).<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4t7n8vtx" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>