Copper‐Catalyzed Trifluoromethylation–Cyclization of Enynes: Highly Regioselective Construction of Trifluoromethylated Carbocycles and Heterocycles. Issue 43 (23rd September 2013) - Gao, Pin
Abstract Regioselective trifluoromethylation–cyclization: A method for copper‐catalyzed trifluoromethylation–cyclization of simple enynes using the CC triple bond as a nucleophile is reported for the first time (see scheme). The reaction proceeds efficiently in a highly regioselective manner to give various 5‐ or 6‐exo‐dig carbocycles and heterocycles in moderate to high yields.