Left atrial appendage occlusion in octogenarians. Issue 5 (24th December 2013)

• Record Type: Journal Article
• Authors: Gafoor, Sameer; Franke, Jennifer; Bertog, Stefan; Boehm, Patrick; Heuer, Luisa; Gonzaga, Maik; Bauer, Janine; Braut, Annkathrin; Lam, Simon; Vaskelyte, Laura; Hofmann, Ilona; Sievert, Horst
• Is Part Of: Catheterization and cardiovascular interventions. Volume 83:Issue 5(2014:Apr. 01)
• Page Start: 805
• Page End: 810
• Publication Date: 2013-12-24
• Subjects: Heart -- Diseases -- Diagnosis -- Periodicals; Cardiac catheterization -- Periodicals; 616.1207572
• DOI: 10.1002/ccd.25297
• Languages: English
• ISSNs: 1522-1946

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="ccd25297-sec-0001" sec-type="section"> <title>Objectives</title> <p>To determine the procedural safety, safety, and efficacy of left atrial appendage (LAA) occlusion in octogenarians.</p> </sec> <sec id="ccd25297-sec-0002" sec-type="section"> <title>Background</title> <p>Elderly patients with atrial fibrillation (AF) often do not receive appropriate anticoagulation. LAA occlusion is an option for patients with AF and contraindications to anticoagulation. Not much is known about the procedural safety and clinical efficacy of LAA occlusion in the very elderly.</p> </sec> <sec id="ccd25297-sec-0003" sec-type="section"> <title>Methods</title> <p>A retrospective review of LAA cases at our institution between 2002 and 2013 in patients 80 years of age or older was performed. Demographic, echocardiographic, procedural, and clinical follow‐up data were collected.</p> </sec> <sec id="ccd25297-sec-0004" sec-type="section"> <title>Results</title> <p>Seventy‐five cases were attempted in patients 80 years of age or older (average age 83.4 ± 2.8 years, 53.3% males). Hypertension, coronary artery disease, and heart failure were present in 96, 41.3, and 36%, respectively. Mean CHADS2 and CHA2DS‐VASc scores were 3.3 and 5.2. Devices used included the WATCHMAN, ACP, PLAATO, Lariat, and Coherex devices, which were attempted in 34.7, 36, 17.3, 5.3, and 5.3%, respectively. Overall procedural success, safety endpoint, and 1‐year device efficacy was 90.1, 3.9, and 97.4%, respectively.</p> </sec> <sec id="ccd25297-sec-0005" sec-type="section"> <title>Conclusion</title> <p>LAA closure is a safe and efficacious method of stroke prevention in the very elderly with AF. © 2013 Wiley Periodicals, Inc.</p> </sec> </abstract>