Borderline trend towards long‐term mortality benefit from drug eluting stents implantation in ST‐elevation myocardial infarction patients in Poland—data from NRDES registry. Issue 3 (23rd September 2013)

• Record Type: Journal Article
• Authors: Siudak, Zbigniew; Dziewierz, Artur; Rakowski, Tomasz; Żmudka, Krzysztof; Legutko, Jacek; Bartuś, Stanisław; Dragan, Jacek; Zasada, Wojciech; Tokarek, Tomasz; Kułaga, Tomasz; Partyka, Łukasz; Dudek, Dariusz
• Is Part Of: Catheterization and cardiovascular interventions. Volume 83:Issue 3(2014:Feb. 15)
• Page Start: 436
• Page End: 442
• Publication Date: 2013-09-23
• Subjects: Heart -- Diseases -- Diagnosis -- Periodicals; Cardiac catheterization -- Periodicals; 616.1207572
• DOI: 10.1002/ccd.25169
• Languages: English
• ISSNs: 1522-1946

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="ccd25169-sec-0001" sec-type="section"> <title>Objectives</title> <p>To analyze long‐term outcome of ST‐Elevation Myocardial Infarction (STEMI) and non‐STEMI (NSTEMI) patients treated with Drug Eluting Stents (DES) stents with regard to mortality and stent thrombosis rates based on the national Polish PCI registry database.</p> </sec> <sec id="ccd25169-sec-0002" sec-type="section"> <title>Background</title> <p>Only a few studies suggested potential trend towards lower mortality in STEMI patients treated with DES. Current European Society of Cardiology STEMI guidelines recommend DES use only with one restriction to suspected patient poor compliance or contraindication to dual antiplatelet therapy.</p> </sec> <sec id="ccd25169-sec-0003" sec-type="section"> <title>Methods</title> <p>Thirteen high‐volume interventional cardiology centers in Poland enrolled patients in National Registry of Drug Eluting Stents (NRDES) Registry from October 2010 till October 2011.</p> </sec> <sec id="ccd25169-sec-0004" sec-type="section"> <title>Results</title> <p>There were 2686 patients enrolled in NRDES Registry. Eighty five patients (3%) had both DES and BMS implanted at index PCI procedure and were excluded from further analysis. A subpopulation of STEMI (1709; 66%) and NSTEMI (892; 34%) patients was selected for BMS vs DES comparison. A significant difference in favor of DES group for 1‐year mortality was found in STEMI subgroup (<italic>P</italic> < 0.0001—unadjusted and <italic>P</italic> = 0.0497 after propensity score adjustment). No such differences were noticed for NSTEMI subgroup or stent thrombosis comparisons.</p> </sec> <sec id="ccd25169-sec-0005" sec-type="section"> <title>Conclusions</title> <p>A strong selection bias for DES stents was observed with regard to demographic and angiographic characteristics in both STEMI and NSTEMI. DES implantation was associated with similar ischemic outcome to BMS at 1‐year follow‐up. STEMI patients with DES presented a trend towards lower long‐term mortality at 1 year in comparison to BMS. © 2013 Wiley Periodicals, Inc.</p> </sec> </abstract>