A sensitive method for the determination of levamisole in serum by electrochemiluminescence. (7th May 2013)

• Record Type: Journal Article
• Authors: Xiao, Ying; Li, Jianping; Fu, Cong
• Is Part Of: Luminescence. Volume 29:Number 2(2014:Mar./Apr.)
• Page Start: 183
• Page End: 187
• Publication Date: 2013-05-07
• Subjects: Luminescence -- Periodicals; Bioluminescence -- Periodicals; Chemiluminescence -- Periodicals; Luminescence -- Periodicals; 535.35
• DOI: 10.1002/bio.2527
• Languages: English
• ISSNs: 1522-7235

Abstract

<abstract abstract-type="main"> <title>ABSTRACT</title> <p>A novel method was developed for the determination of levamisole by electrochemiluminescence. The method was based on electrochemiluminescence signal enhancement produced by Ru(bpy)₃²⁺, which reacted with the tertiary amine group of levamisole on a platinum electrode in 12 mmol/L borate buffer (pH 9). A linear relationship between the luminous intensity and concentration of levamisole in the range 0–1 × 10^–7 mol/L was obtained and the detection limit was 1.76 × 10^–11 mol/L. The method is sensitive, selective, simple and convenient. The method has been successfully applied to the analysis of levamisole in serum. Copyright © 2013 John Wiley &amp; Sons, Ltd.</p> </abstract>