Highly Enantioselective Hydrogenation of 2, 4‐Diaryl‐1, 5‐Benzodiazepines Catalyzed by Dendritic Phosphinooxazoline Iridium Complexes. Issue 6 (28th March 2013)

• Record Type: Journal Article
• Authors: Ma, Baode; Ding, Ziyuan; Liu, Ji; He, Yanmei; Fan, Qing‐Hua
• Is Part Of: Chemistry, an Asian journal. Volume 8:Issue 6(2013:Jun.)
• Page Start: 1101
• Page End: 1104
• Publication Date: 2013-03-28
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1002/asia.201300150
• Languages: English
• ISSNs: 1861-4728

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>A PHOX with arms</bold>: A series of dendrimers with Ir phosphinooxazoline (PHOX) cores were designed and synthesized and found to be highly effective and recoverable catalysts for asymmetric hydrogenation of 2, 4‐diaryl‐1, 5‐benzodiazepines. An obvious positive dendritic effect on reactivity was observed, leading to chiral nitrogen‐containing heterocycles with excellent enantioselectivities.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4t78ftb5" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>