Cover Picture: Binding of a Designed Anti‐Cancer Drug to the Central Cavity of an RNA Three‐Way Junction (Angew. Chem. Int. Ed. 44/2013). Issue 44 (2nd October 2013)

• Record Type: Journal Article
• Authors: Phongtongpasuk, Siriporn; Paulus, Susann; Schnabl, Joachim; Sigel, Roland K. O.; Spingler, Bernhard; Hannon, Michael J.; Freisinger, Eva
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 44(2013)
• Page Start: 11427
• Page End: 11427
• Publication Date: 2013-10-02
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201308234
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <italic> <bold>Recognition and stabilization</bold> </italic> of an RNA three‐way junction by a supramolecular di‐iron(II) cylindrical complex is described by R. K. O. Sigel, B. Spingler, M. J. Hannon, E. Freisinger et al. in their Communication on <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">page 11513 ff.</ext-link> This potential anti‐cancer metal‐based drug fits perfectly into the central RNA core and stabilizes this architecture in the solid state as well as under native gel conditions. (Cover picture: Joachim Schnabl.)<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4t6z7f38" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>