Copper(I)‐Catalyzed Alkylation of Aryl‐ and Alkenylsilanes Activated by Intramolecular Coordination of an Alkoxide1. Issue 48 (9th October 2013)

• Record Type: Journal Article
• Authors: Tsubouchi, Akira; Muramatsu, Daisuke; Takeda, Takeshi
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 48(2013)
• Page Start: 12719
• Page End: 12722
• Publication Date: 2013-10-09
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201306882
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Let's coordinate</bold>: Copper(I)‐catalyzed cross‐coupling of alkenyl‐ and arylsilanes with primary alkyl iodides as well as allylic and benzylic halides as C(sp³)X electrophilic coupling partners has been realized by intramolecular activation through alkoxide coordination. This alkylation tolerates a range of functional groups including a free hydroxy group. IPr=1, 3‐bis(2, 6‐diisopropylphenyl)imidazol‐2‐ylidene.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4t7bqnmr" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>