Highly Enantioselective Bromocyclization of Tryptamines and Its Application in the Synthesis of (−)‐Chimonanthine1. Issue 49 (10th October 2013) - Xie, Weiqing
Abstract A shorter path: A highly enantioselective bromocyclization of tryptamine has been developed using an anionic chiral phase‐transfer catalyst. This method provides a direct approach for preparing chiral 3‐bromopyrroloindoline from tryptamine, which enables a four‐step enantioselective synthesis of (−)‐chimonanthine. PG=protecting group.