Indole Synthesis by Rhodium(III)‐Catalyzed Hydrazine‐Directed CH Activation: Redox‐Neutral and Traceless by NN Bond Cleavage1. Issue 47 (25th September 2013)

• Record Type: Journal Article
• Authors: Zhao, Dongbing; Shi, Zhuangzhi; Glorius, Frank
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 47(2013)
• Page Start: 12426
• Page End: 12429
• Publication Date: 2013-09-25
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201306098
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Fishing for compl<italic>e</italic>ments!</bold> There is an alternative to the useful Fischer indole synthesis. The new method utilizes the same retrosynthetic disconnection but is based on a Rh^III‐catalyzed directed CH activation step and a successive coupling with alkynes.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4t78stb0" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>