Comparative study of the effect of 50% pyruvic and 30% salicylic peels on the skin lipid film in patients with acne vulgaris. (March 2014)

• Record Type: Journal Article
• Authors: Marczyk, Beata; Mucha, Paulina; Budzisz, Elżbieta; Rotsztejn, Helena
• Is Part Of: Journal of cosmetic dermatology. Volume 13:Number 1(2014:Mar.)
• Page Start: 15
• Page End: 21
• Publication Date: 2014-03
• Subjects: Skin -- Diseases -- Treatment -- Periodicals; Lasers in surgery -- Periodicals; Skin -- Pathophysiology -- Periodicals; Surgery, Plastic -- Periodicals; 616.5
• DOI: 10.1111/jocd.12050
• Languages: English
• ISSNs: 1473-2130

Abstract

<abstract abstract-type="main" id="jocd12050-abs-0001"> <title>Summary</title> <sec id="jocd12050-sec-0001" sec-type="section"> <p>Pyruvic (alfa‐keto acid) and salicylic (beta<italic>‐</italic>hydroxy acid) acids are superficial peels frequently used in patients with acne vulgaris.</p> </sec> <sec id="jocd12050-sec-0002" sec-type="section"> <title>Aim</title> <p>The aim of the study was to compare the effect of 50% pyruvic and 30% salicylic peels on facial sebum secretion in patients with acne vulgaris, aged 13–30.</p> </sec> <sec id="jocd12050-sec-0003" sec-type="section"> <title>Material and methods</title> <p>The level of secreted sebum was determined in 20 men and women. Ten patients were treated with 50% pyruvic acid and the remaining 10 with 30% salicylic acid. Each peel was applied five times at 2‐week intervals. The sebum measurements were taken in the T‐ and U‐zones using a Sebumeter SM 815 (Courage & Khazaka, Germany). The last, sixth measurement was taken 2 weeks after the treatment.</p> </sec> <sec id="jocd12050-sec-0004" sec-type="section"> <title>Results</title> <p>A statistically significant decrease in the level of secreted sebum in both U‐ and T‐ zones was observed in the patients studied after the third application of 50% pyruvic peel and the second application of 30% salicylic peel. Two weeks following the completion of therapy, sebumetric measurements demonstrated a greater reduction in the facial skin lipid film among the patients treated with salicylic peel.</p> </sec> <sec id="jocd12050-sec-0005" sec-type="section"> <title>Conclusions</title> <p>Peels with 50% pyruvic acid and 30% salicylic acid are the procedures that significantly contributed to a decrease in the level of secreted sebum on the facial skin surface in the group of patients studied. A greater therapeutic effect was observed following 30% salicylic peel, which might be associated with its high lipophilic properties and easier penetration through the lipid barriers of the epidermis.</p> </sec> </abstract>