Endoscopic resection for duodenal carcinoid tumors: A multicenter, retrospective study. Issue 2 (February 2014)

• Record Type: Journal Article
• Authors: Kim, Gwang Ha; Kim, Jin Il; Jeon, Seong Woo; Moon, Jeong Seop; Chung, Il‐Kwun; Jee, Sam‐Ryong; Kim, Heung Up; Seo, Geom Seog; Baik, Gwang Ho; Lee, Yong Chan
• Is Part Of: Journal of gastroenterology and hepatology. Volume 29:Issue 2(2014:Feb.)
• Page Start: 318
• Page End: 324
• Publication Date: 2014-02
• Subjects: Gastroenterology -- Periodicals; Digestive organs -- Diseases -- Periodicals; Liver -- Diseases -- Periodicals; Gastroenterology -- Periodicals; Liver Diseases -- Periodicals; 616.33
• DOI: 10.1111/jgh.12390
• Languages: English
• ISSNs: 0815-9319

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="jgh12390-sec-0001" sec-type="section"> <title>Background and Aim</title> <p>Gastrointestinal carcinoid tumors < 10 mm in diameter and limited to the submucosal layer demonstrate a low frequency of lymph node and distant metastasis, and are suitable for endoscopic treatment. The aim of this study was to assess the efficacy, safety, and long‐term prognosis of endoscopic resections for the treatment of duodenal carcinoid tumors.</p> </sec> <sec id="jgh12390-sec-0002" sec-type="section"> <title>Methods</title> <p>This study included a total of 41 duodenal carcinoid tumors in 38 patients between January 2006 and December 2011. The indications for endoscopic resection were lesions ≤ 10 mm in diameter, confined to the submucosal layer, and without lymph node or distant metastasis. Endoscopic resection was accomplished using endoscopic mucosal resection (EMR), EMR with a ligation device (EMR‐L), EMR after circumferential precutting, or endoscopic submucosal dissection (ESD).</p> </sec> <sec id="jgh12390-sec-0003" sec-type="section"> <title>Results</title> <p>EMR was performed in 18 tumors, EMR‐L in 16, EMR after circumferential precutting in 3, and ESD in 4. <italic>En‐bloc</italic> resection was performed in 39 tumors (95%), and endoscopic complete resection was achieved in 40 (98%); pathological complete resection was achieved in 17 tumors (41%). The endoscopic complete resection rate did not differ according to the resection method, but the pathological complete resection rate was higher for ESD than for EMR and EMR‐L. Intraprocedural bleeding was noted in five cases, with no occurrence of perforation. Recurrence was not observed during the mean follow‐up period of 17 months (range 1–53 months).</p> </sec> <sec id="jgh12390-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Endoscopic resection appears to be a safe and effective treatment for duodenal carcinoid tumors measuring ≤ 10 mm in diameter and confined to the submucosal layer.</p> </sec> </abstract>