Interactive effects of an isocaloric high‐protein diet and resistance exercise on body composition, ghrelin, and metabolic and hormonal parameters in untrained young men: A randomized clinical trial. Issue 2 (10th October 2013)

• Record Type: Journal Article
• Authors: Kim, Hyun Ho; Kim, Yun Jin; Lee, Sang Yeoup; Jeong, Dong Wook; Lee, Jeong Gyu; Yi, Yu Hyone; Cho, Young Hye; Choi, Eun Jung; Kim, Hyun Jun
• Is Part Of: Journal of diabetes investigation. Volume 5:Issue 2(2014:Apr.)
• Page Start: 242
• Page End: 247
• Publication Date: 2013-10-10
• Subjects: Diabetes -- Periodicals; Diabetes -- Research -- Periodicals; Diabetes Mellitus -- Periodicals; 616.462005
• DOI: 10.1111/jdi.12148
• Languages: English
• ISSNs: 2040-1116

Abstract

<abstract abstract-type="main" id="jdi12148-abs-0001"> <title>Abstract</title> <sec id="jdi12148-sec-0001" sec-type="section"> <title>Aims/Introduction</title> <p>The interactive effects of resistance training and dietary protein on hormonal responses in adults are not clear and remain controversial. We tested the effect of an isocaloric high‐protein diet on body composition, ghrelin, and metabolic and hormonal parameters during a 12‐week resistance training program in untrained healthy young men.</p> </sec> <sec id="jdi12148-sec-0002" sec-type="section"> <title>Material and Methods</title> <p>We randomized 18 healthy young men to a standard diet (ST group) or an isocaloric high protein diet (HP group). Both groups participated in a 12‐week resistance exercise program. We measured body composition, lipid profile, homeostatic model assessment of insulin resistance (HOMA‐IR) indices, total ghrelin, and exercise‐related hormones at baseline and 12 weeks.</p> </sec> <sec id="jdi12148-sec-0003" sec-type="section"> <title>Results</title> <p>In the HP group, lean body mass (LBM), total ghrelin, growth hormone, testosterone and cortisol levels showed an increase, whereas body fat percentage and HOMA‐IR showed a decrease at 12 weeks, compared with baseline (<italic>P</italic> ≤ 0.05). In the ST group, no changes in these parameters were observed during the 12‐week period. During the 12‐week period, significant differences in the pattern of change of LBM (<italic>P</italic> = 0.032), total ghrelin (<italic>P</italic> = 0.037), HOMA‐IR (<italic>P</italic> = 0.040) and high‐density lipoprotein cholesterol (<italic>P</italic> = 0.011) over time were observed between the groups.</p> </sec> <sec id="jdi12148-sec-0004" sec-type="section"> <title>Conclusions</title> <p>The findings of the present study suggest that an isocaloric high‐protein diet can ameliorate body composition, metabolic profiles and energy metabolism during a 12‐week scheduled resistance training program in untrained healthy young men. This trial was registered with <ext-link ext-link-type="uri" xlink:href="http://ClinicalTrials.gov" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">ClinicalTrials.gov</ext-link> (no. NCT01714700).</p> </sec> </abstract>