Quality of life of patients with epilepsy in Malaysia. (18th April 2012)

• Record Type: Journal Article
• Authors: Mohamed, Salina; Gill, Jesjeet Singh; Tan, Chong Tin
• Is Part Of: Asia-Pacific psychiatry. Volume 6:Number 1(2014:Mar.)
• Page Start: 105
• Page End: 109
• Publication Date: 2012-04-18
• Subjects: Psychiatry -- Pacific Area -- Periodicals; 616.890095
• DOI: 10.1111/j.1758-5872.2012.00192.x
• Languages: English
• ISSNs: 1758-5864

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="appy192-sec-0001" sec-type="section"> <title>Introduction</title> <p>To determine the quality of life of patients with epilepsy and its relationship with depression, and the clinical and sociodemographic variables.</p> </sec> <sec id="appy192-sec-0002" sec-type="section"> <title>Methods</title> <p>This was a cross‐sectional study in which a total of 120 epilepsy patients were recruited from a neurology outpatient clinic. Sociodemographic and clinical variables were recorded. Hospital Anxiety and Depression Scale (HADS) and Mini International Neuropsychiatric Interview (M.I.N.I.) were used to screen and diagnose for depression, respectively. Quality of Life Inventory of Epilepsy (QOLIE‐31) was used to assess quality of life.</p> </sec> <sec id="appy192-sec-0003" sec-type="section"> <title>Results</title> <p>Patients with epilepsy with major depression had poorer quality life (36.4 ± 1.8) compared to those without depression (41.7 ± 3.8, <italic>P</italic> < 0.001). Depression, having one seizure or more per month and having seizures within one month of interview were correlated with poorer quality of life, <italic>P</italic> < 0.001. Multivariate linear regression analyses showed that depression and recent seizures predicted having poorer quality of life in patients with epilepsy.</p> </sec> <sec id="appy192-sec-0004" sec-type="section"> <title>Discussion</title> <p>Depression and poor seizure control were predictors for poor quality of life in patients with epilepsy. Therefore, epilepsy patients should be regularly screened for depression and treatment for epilepsy must be optimized to minimize the negative impact of having epilepsy for these patients.</p> </sec> </abstract>