Healing of Fresh Extraction Sockets Filled with Bioactive Glass Particles: Histological Findings in Humans. (12th June 2012)

• Record Type: Journal Article
• Authors: Clozza, Emanuele; Pea, Maurizio; Cavalli, Fabio; Moimas, Loredana; Di Lenarda, Roberto; Biasotto, Matteo
• Is Part Of: Clinical implant dentistry and related research. Volume 16:Number 1(2014:Feb.)
• Page Start: 145
• Page End: 153
• Publication Date: 2012-06-12
• Subjects: Dental implants -- Periodicals; Dental Implantation -- Periodicals; Dental Implants -- Periodicals; 617.693
• DOI: 10.1111/j.1708-8208.2012.00463.x
• Languages: English
• ISSNs: 1523-0899

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>ABSTRACT</title> <p> <bold>Purpose:</bold> The aim of the present study was to histologically evaluate fresh human sockets filled with bioactive glass after 6 months of healing.</p> <p> <bold>Materials and Methods:</bold> In 13 patients, 32 single extraction sites in the anterior area underwent socket ridge preservation procedure (RPP) with a bioactive glass (BioRestore™, Inion Oy, Tampere, Finland). At implant installation, 22 bone cores were trephined out and processed for histomorphometric and immunohistochemical analysis.</p> <p> <bold>Results:</bold> Newly formed immature bone around residual particles of bioactive glass was found in all 22 biopsies. The histomorphometry of the amount of bone, provisional matrix, and residual graft returned a mean ± SD value of 54 ± 31%, 37.9 ± 25.6%, and 8.1 ± 7.8, respectively, 6 months after RPP.</p> <p> <bold>Conclusion:</bold> The use of this grafting material in fresh extraction sockets appears to delay the healing processes of the alveolar bone; therefore, its indication as a material for RPP when implant placement is considered within 6 months after extraction should be revised.</p> </abstract>