Evaluating of Small Intracranial Aneurysms by 64‐Detector CT Angiography: A Comparison with 3‐Dimensional Rotation DSA or Surgical Findings. Issue 2 (10th December 2012)

• Record Type: Journal Article
• Authors: Zhang, He; Hou, Chang; Zhou, Zhi; Zhang, Hao; Zhou, Gen; Zhang, Gui
• Is Part Of: Journal of neuroimaging. Volume 24:Issue 2(2014)
• Page Start: 137
• Page End: 143
• Publication Date: 2012-12-10
• Subjects: Diagnostic imaging -- Periodicals; Nervous system -- Diseases -- Diagnosis -- Periodicals; Imagerie pour le diagnostic -- Périodiques; Système nerveux -- Maladies -- Diagnostic -- Périodiques; Imagerie médicale; Neuroimagerie; Neurologie; Système nerveux; Périodique électronique (Descripteur de forme); Ressource Internet (Descripteur de forme); 616.804754
• DOI: 10.1111/j.1552-6569.2012.00747.x
• Languages: English
• ISSNs: 1051-2284

Abstract

<abstract abstract-type="main"> <title>ABSTRACT</title> <sec id="jon747-sec-0010" sec-type="section"> <title>BACKGROUND AND PURPOSE</title> <p>The diagnostic performance of 64‐detector computed tomographic angiography (CTA) for detection of small intracranial aneurysms (SIAs) was evaluated.</p> </sec> <sec id="jon747-sec-0020" sec-type="section"> <title>METHODS</title> <p>In this prospective study, 112 consecutive patients underwent 64‐detector CTA before volume‐rendering rotation digital subtraction angiography (VR‐RDSA) or surgery. VR‐RDSA or intraoperative findings or both were used as the gold standards. The accuracy, sensitivity, specificity, and positive predictive values (PPV) and negative predictive values (NPV), as measures to detect or rule out SIAs, were determined by patient‐based and aneurysm size‐based evaluations.</p> </sec> <sec id="jon747-sec-0030" sec-type="section"> <title>RESULTS</title> <p>The reference standard methods revealed 84 small aneurysms in 71 patients. The results of patient‐based 64‐detector CTA evaluation for SIAs were: accuracy, 98.2%; sensitivity, 98.6%; specificity, 97.6%; PPV, 98.6%; and NPV, 97.6%. The aneurysm‐based evaluation results were: accuracy, 96.8%; sensitivity, 97.6%; specificity, 95.1%; PPV, 97.6%; and NPV, 95.1%. Two false‐positive and two false‐negative findings for aneurysms <3 mm in size occurred in the 64‐detector CTA analysis.</p> </sec> <sec id="jon747-sec-0040" sec-type="section"> <title>CONCLUSION</title> <p>The diagnostic performance of 64‐detector CTA did not improve much compared with 16‐detector CTA for detecting SIAs, especially for very small aneurysms. VR‐RDSA is still necessary for patients with a history of subarachnoid hemorrhage if the CTA findings are negative.</p> </sec> </abstract>