Cleaning and asthma characteristics in women. Issue 3 (19th August 2013)

• Record Type: Journal Article
• Authors: Dumas, Orianne; Siroux, Valérie; Luu, Frédéric; Nadif, Rachel; Zock, Jan‐Paul; Kauffmann, Francine; Le Moual, Nicole
• Is Part Of: American journal of industrial medicine. Volume 57:Issue 3(2014:Mar.)
• Page Start: 303
• Page End: 311
• Publication Date: 2013-08-19
• Subjects: Medicine, Industrial -- Periodicals; Médecine du travail -- Périodiques; 616.9803
• DOI: 10.1002/ajim.22244
• Languages: English
• ISSNs: 0271-3586

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <sec id="ajim22244-sec-0001" sec-type="section"> <title>Background</title> <p> <italic>We aimed to assess the associations between occupational exposure to cleaning products, a gender‐related exposure, and asthma characteristics, considering clinical, immunological and inflammatory aspects</italic>.</p> </sec> <sec id="ajim22244-sec-0002" sec-type="section"> <title>Methods</title> <p> <italic>Analyses were conducted in 391 women (73 with adult‐onset asthma) from the follow‐up of the Epidemiological Study on the Genetics and Environment of Asthma (EGEA). Occupational exposure to cleaning/disinfecting products was estimated using the asthma‐specific job‐exposure‐matrix (44 women exposed)</italic>.</p> </sec> <sec id="ajim22244-sec-0003" sec-type="section"> <title>Results</title> <p> <italic>Occupational exposures were associated with more symptomatic asthma (odds ratio (95% CI): 2.8(1.2–6.4)) and severe asthma (5.1(1.7–15.3)). An association was suggested for poorly controlled asthma (2.2(0.9–5.5)). Associations were observed for asthma without positive skin prick test (3.0(1.1–8.3)), with a low IgE level (2.8(1.2–6.2)), and with a low eosinophil count (3.2(1.5–7.1))</italic>.</p> </sec> <sec id="ajim22244-sec-0004" sec-type="section"> <title>Conclusions</title> <p> <italic>Results strengthen the evidence of a deleterious role of cleaning products in asthma and are consistent with the hypothesis of non‐allergic mechanisms in relation to workplace cleaning exposures</italic>. Am. J. Ind. Med. 57:303–311, 2014. © 2013 Wiley Periodicals, Inc.</p> </sec> </abstract>