Eosinophilic fasciitis associated with hypereosinophilia, abnormal bone‐marrow karyotype and inversion of chromosome 5. (16th November 2013)

• Record Type: Journal Article
• Authors: Ferguson, J. S.; Bosworth, J.; Min, T.; Mercieca, J.; Holden, C. A.
• Is Part Of: Clinical and experimental dermatology. Volume 39:Number 2(2014)
• Page Start: 150
• Page End: 153
• Publication Date: 2013-11-16
• Subjects: Skin -- Diseases -- Periodicals; 616.5
• DOI: 10.1111/ced.12228
• Languages: English
• ISSNs: 0307-6938

Abstract

<abstract abstract-type="main" id="ced12228-abs-0001"> <title>Summary</title> <p>We report the case of a male patient presenting with eosinophilia, pulmonary oedema and eosinophilic fasciitis (EF). He had the classic clinical appearance and magnetic resonance imaging of EF. Cytogenetic analysis of the bone marrow revealed a previously undescribed pericentric inversion of chromosome 5. Overall, the presentation was consistent with a diagnosis of chronic eosinophilic leukaemia, not otherwise specified (CEL‐NOS). Dermatologists should consult a haematologist in cases of EF, in order to rule out possible haematological malignancies.</p> </abstract>