The Iron(II) Complex [Fe(CF3SO3)2(mcp)] as a Convenient, Readily Available Catalyst for the Selective Oxidation of Methylenic Sites in Alkanes. Issue 4 (6th February 2014)

• Record Type: Journal Article
• Authors: Canta, Mercè; Font, David; Gómez, Laura; Ribas, Xavi; Costas, Miquel
• Is Part Of: Advanced synthesis & catalysis. Volume 356:Issue 4(2014)
• Page Start: 818
• Page End: 830
• Publication Date: 2014-02-06
• Subjects: Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201300923
• Languages: English
• ISSNs: 1615-4150

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The efficient and selective oxidation of secondary CH sites of alkanes is achieved by using low catalyst loadings of a non‐expensive, readily available iron catalyst [Fe(II)(CF₃SO₃)₂(mcp)], {<bold>Fe‐mcp</bold>, [mcp=<italic>N</italic>, <italic>N′‐</italic>dimethyl‐<italic>N</italic>, <italic>N′</italic>‐bis(2‐pyridylmethyl)cyclohexane‐<italic>tran</italic>s‐1, 2‐diamine]}, and hydrogen peroxide (H₂O₂) as oxidant, <italic>via</italic> a simple reaction protocol. Natural products are selectively oxidized and isolated in synthetically amenable yields. The easy access to large quantities of the catalyst and the simplicity of the CH oxidation procedure make this system a particularly convenient tool to carry out alkane CH oxidation reactions on the preparative scale, and in short reaction times.</p> <p> <boxed-text content-type="graphic" position="anchor" orientation="portrait"> <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4sx5zzmf" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /> </boxed-text> </p> </abstract>