Molecular Iodine‐Mediated Domino Reaction for the Synthesis of Benzamides, 2, 2‐Diazidobenzofuran‐3(2H)‐ones and Benzoxazolones. Issue 18 (12th December 2013)

• Record Type: Journal Article
• Authors: Rajendar, K.; Kant, Ruchir; Narender, T.
• Is Part Of: Advanced synthesis & catalysis. Volume 355:Issue 18(2013)
• Page Start: 3591
• Page End: 3596
• Publication Date: 2013-12-12
• Subjects: Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201300668
• Languages: English
• ISSNs: 1615-4150

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A simple and efficient domino protocol has been developed for the preparation of biologically important benzamides, 2, 2‐diazidobenzofuran‐3(2<italic>H</italic>)‐ones and benzoxazolones from various structurally and electronically divergent acetophenones and <italic>ortho</italic>‐hydroxyacetophenones in the presence of molecular iodine, sodium azide and sodium bicarbonate at 100 °C in good to excellent yields.</p> <p> <boxed-text content-type="graphic" position="anchor" orientation="portrait"> <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4t37w6v9" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /> </boxed-text> </p> </abstract>