Increased number and frequency of group 3 innate lymphoid cells in nonlesional psoriatic skin. (March 2014)

• Record Type: Journal Article
• Authors: Dyring‐Andersen, B.; Geisler, C.; Agerbeck, C.; Lauritsen, J.P.H.; Gúdjonsdottir, S.D.; Skov, L.; Bonefeld, C.M.
• Is Part Of: British journal of dermatology. Volume 170:Number 3(2014:Mar.)
• Page Start: 609
• Page End: 616
• Publication Date: 2014-03
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Periodicals; 616.5
• DOI: 10.1111/bjd.12658
• Languages: English
• ISSNs: 0007-0963

Abstract

<abstract abstract-type="short" xml:lang="en" id="bjd12658-abs-0002"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>What's already known about this topic?</bold> </p> <p> <list id="bjd12658-list-0001" list-type="bullet"> <list-item> <p>The interleukin (IL)‐23/Th17 axis is important for the pathogenesis of psoriasis. Innate lymphoid cells producing IL‐17 and/or IL‐22 are known to be involved in the pathogenesis of psoriasis.</p> </list-item> </list> </p> <p> <bold>What does this study add?</bold> </p> <p> <list id="bjd12658-list-0002" list-type="bullet"> <list-item> <p>An increased frequency of group 3 innate lymphoid cells is found in noninvolved psoriatic skin compared with healthy skin, which may indicate that these cells contribute to psoriasis development.</p> </list-item> </list> </p> </abstract>