Antimicrobial susceptibility profile of Acinetobacter species isolated from blood cultures in two Japanese university hospitals. (February 2014)

• Record Type: Journal Article
• Authors: Kishii, Kozue; Kikuchi, Ken; Yoshida, Atsushi; Okuzumi, Katsuko; Uetera, Yushi; Yasuhara, Hiroshi; Moriya, Kyoji
• Is Part Of: Microbiology and immunology. Volume 58:Number 2(2014:Feb.)
• Page Start: 142
• Page End: 146
• Publication Date: 2014-02
• Subjects: Microbiology -- Periodicals; Immunology -- Periodicals; Allergy and Immunology -- Periodicals; Microbiology -- Periodicals; Microbiologie -- Périodiques; Immunologie -- Périodiques; 579
• DOI: 10.1111/1348-0421.12117
• Languages: English
• ISSNs: 0385-5600

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>ABSTRACT</title> <sec id="mim12117-sec-0001" sec-type="section"> <p>Carbapenem‐resistant <italic>Acinetobacter baumannii</italic> has rapidly spread worldwide. This study investigated antibiotic susceptibility and genotypic resistance of 123 consecutive blood culture isolates of <italic>Acinetobacter</italic> species collected between 2003 and 2011 in two Japanese hospitals. The isolates were assigned to 13 species. Carbapenem resistance was detected in four isolates. Only one <italic>A. baumannii</italic> isolate had <italic>bla</italic>_OXA‐23 together with IS<italic>Aba1</italic>; the remaining three isolates had IMP‐1 metallo‐β‐lactamase. Quinolone resistance was detected in five isolates that had point mutations in the quinolone resistance‐determining region. The predominance of various non‐<italic>A. baumannii</italic> species and low prevalence of carbapenem resistance among blood culture isolates of <italic>Acinetobacter</italic> species in two Japanese hospitals were confirmed.</p> </sec> </abstract>