Characteristic systemic cytokine responses in children with human bocavirus‐positive lower respiratory tract infection. (March 2014)

• Record Type: Journal Article
• Authors: Hirose, Yosuke; Hamada, Hiromichi; Wakui, Taku; Ogawa, Tomoko; Terai, Masaru
• Is Part Of: Microbiology and immunology. Volume 58:Number 3(2014:Mar.)
• Page Start: 215
• Page End: 218
• Publication Date: 2014-03
• Subjects: Microbiology -- Periodicals; Immunology -- Periodicals; Allergy and Immunology -- Periodicals; Microbiology -- Periodicals; Microbiologie -- Périodiques; Immunologie -- Périodiques; 579
• DOI: 10.1111/1348-0421.12132
• Languages: English
• ISSNs: 0385-5600

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>ABSTRACT</title> <sec id="mim12132-sec-0001" sec-type="section"> <p>To investigate systemic cytokine responses in human bocavirus (HBoV)‐associated lower respiratory tract infection, serum cytokine profiles were analyzed in HBoV positive‐children (<italic>n</italic> = 14) using multiplex immunoassay. Concentrations of TNF‐α, IL‐2, IL‐5 and IL‐8 on admission were significantly different from those of respiratory syncytial virus‐positive children (<italic>n</italic> = 28). This unique cytokine response might partly explain some characteristic clinical features of HBoV‐associated respiratory infection.</p> </sec> </abstract>