Graphene‒Regulated Cardiomyogenic Differentiation Process of Mesenchymal Stem Cells by Enhancing the Expression of Extracellular Matrix Proteins and Cell Signaling Molecules. Issue 2 (15th August 2013)

• Record Type: Journal Article
• Authors: Park, Jooyeon; Park, Subeom; Ryu, Seungmi; Bhang, Suk Ho; Kim, Jangho; Yoon, Jeong‐Kee; Park, Yoon Hwan; Cho, Sung‐Pyo; Lee, Seahyoung; Hong, Byung Hee; Kim, Byung‐Soo
• Is Part Of: Advanced healthcare materials. Volume 3:Issue 2(2014:Feb.)
• Page Start: 176
• Page End: 181
• Publication Date: 2013-08-15
• Subjects: Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201300177
• Languages: English
• ISSNs: 2192-2640

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>The potential of graphene as a mesenchymal stem cell (MSC) culture substrate</bold> to promote cardiomyogenic differentiation is demonstrated. Graphene exhibits no sign of cytotoxicity for stem cell culture. MSCs are committed toward cardiomyogenic lineage by simply culturing them on graphene. This may be attributed, at least partially, to the regulation of expression levels of extracellular matrix and signaling molecules. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4sm1x8c7" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>