Engineering Polymeric Microparticles as Theranostic Carriers for Selective Delivery and Cancer Therapy. Issue 12 (28th May 2013)

• Record Type: Journal Article
• Authors: Win, Khin Yin; Ye, Enyi; Teng, Choon Peng; Jiang, Shan; Han, Ming‐Yong
• Is Part Of: Advanced healthcare materials. Volume 2:Issue 12(2013:Dec.)
• Page Start: 1571
• Page End: 1575
• Publication Date: 2013-05-28
• Subjects: Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201300077
• Languages: English
• ISSNs: 2192-2640

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Multifunctional polymeric nano‐ and microparticles</bold> are engineered as theranostic carriers and their selective size‐dependent cellular uptake is demonstrated. It is found that effective uptake and accumulation of nanoparticles occurs in both normal and cancer cells, whereas, that of microparticles occurs in cancer cells but not in normal cells, allowing cancer cells to be specifically targeted for local drug delivery. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4t38tsk5" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>