Biomedical Applications: Liver‐Specific and Echogenic Hyaluronic Acid Nanoparticles Facilitating Liver Cancer Discrimination (Adv. Funct. Mater. 44/2013). (26th November 2013)

• Record Type: Journal Article
• Authors: Min, Hyun Su; Son, Sejin; Lee, Tae Woong; Koo, Heebeom; Yoon, Hong Yeol; Na, Jin Hee; Choi, Yongseok; Park, Jae Hyung; Lee, Jaeyoung; Han, Moon Hee; Park, Rang‐Woon; Kim, In‐San; Jeong, Seo Young; Rhee, Kyehan; Kim, Sun Hwa; Kwon, Ick Chan; Kim, Kwangmeyung
• Is Part Of: Advanced functional materials. Volume 23:Number 44(2013)
• Page Start: 5453
• Page End: 5453
• Publication Date: 2013-11-26
• Subjects: Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201370223
• Languages: English
• ISSNs: 1616-301X

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">On page 5518</ext-link>, an ultralong‐acting, liver‐specific, ultrasound contrast agent is presented in the form of self‐assembled, echogenic hyaluronic acid nanoparticles. I. C. Kwon, K. Kim, and co‐workers use hydrophobic interactions and an oilin‐water emulsification method to encapsulate bioinert and hydrophobic perfluoropentane as an ultrasound gas precursor into the nanoparticles. These particles are more stable and robust echogenic solid bodies than the conventional microbubbles, with an in vivo favorable hydrodynamic size. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4t6qq5jx" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>