Nanocomposites: Graphene–Ruthenium(II) Complex Composites for Sensitive ECL Immunosensors (Small 4/2014). Issue 4 (February 2014)

• Record Type: Journal Article
• Authors: Xiao, Fang‐Nan; Wang, Min; Wang, Feng‐Bin; Xia, Xing‐Hua
• Is Part Of: Small. Volume 10:Issue 4(2014:Feb.)
• Page Start: 705
• Page End: 705
• Publication Date: 2014-02
• Subjects: Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.201470026
• Languages: English
• ISSNs: 1613-6810

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="smll201470026-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Ru‐PTCA/G nanocomposites are synthesized via a one step synthesis procedure under moderate conditions followed by covalent attachment of an amine derivative Ru(II) complex through amide bond formation. As X.‐H. Xia and co‐workers report on page 706, the product shows good electrochemical activity and ca. 21 times higher luminescence quantum efficiency than the adsorbed Ru(II) complex. A solidstate electrochemiluminescent (ECL) immunosensor is developed based on the Ru‐PTCA/G nanocomposites for sensitive detection of α‐fetoprotein (AFP). The ECL peak intensity in the presence of AFP is much lower than that in the absence of AFP due to the insulating effect of the formed antigen‐antibody complex, which inhibits the electron transfer and the mass transfer of tripropylamine to the surface of the Ru‐PTCA/G modified electrode. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4swsskc4" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>