Exhaustion of Racing Sperm in Nature‐Mimicking Microfluidic Channels During Sorting. Issue 20 (16th May 2013)

• Record Type: Journal Article
• Authors: Tasoglu, Savas; Safaee, Hooman; Zhang, Xiaohui; Kingsley, James L.; Catalano, Paolo N.; Gurkan, Umut Atakan; Nureddin, Aida; Kayaalp, Emre; Anchan, Raymond M.; Maas, Richard L.; Tüzel, Erkan; Demirci, Utkan
• Is Part Of: Small. Volume 9:Issue 20(2013:Oct.)
• Page Start: 3374
• Page End: 3384
• Publication Date: 2013-05-16
• Subjects: Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.201300020
• Languages: English
• ISSNs: 1613-6810

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Fertilization is central to the survival and propagation of a species</bold>, however, the precise mechanisms that regulate the sperm's journey to the egg are not well understood. In nature, the sperm has to swim through the cervical mucus, akin to a microfluidic channel. Inspired by this, a simple, cost‐effective microfluidic channel is designed on the same scale. The experimental results are supported by a computational model incorporating the exhaustion time of sperm. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4t8ddbqq" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>