Induced Adaptation of Bacillus sp. to Antimicrobial Nanosilver. Issue 21 (29th April 2013)

• Record Type: Journal Article
• Authors: Gunawan, Cindy; Teoh, Wey Yang; Marquis, Christopher P.; Amal, Rose
• Is Part Of: Small. Volume 9:Issue 21(2013:Nov.)
• Page Start: 3554
• Page End: 3560
• Publication Date: 2013-04-29
• Subjects: Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.201300761
• Languages: English
• ISSNs: 1613-6810

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>The natural ability of <italic>Bacillus sp.</italic> to adapt to nanosilver cytotoxicity</bold> upon prolonged exposure is reported for the first time. The combined adaptive effects of nanosilver resistance and enhanced growth are induced under various intensities of nanosilver‐stimulated cellular oxidative stress, ranging from only minimal cellular redox imbalance to the lethal levels of cellular ROS stimulation. An important implication of the present work is that such adaptive effects lead to the ultimate domination of nanosilver‐resistant <italic>Bacillus sp.</italic> in the microbiota, to which nanosilver cytotoxicity is continuously applied. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4t8d86c6" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>